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By Damian McNamara, MA July 25, 2022
Cannabidiol (CBD) products made from hemp have gotten more popular in recent years. But how much can you trust what the label says, compared to what really is in CBD patches, creams, and lotions?
A team of investigators decided to find out. They bought 105 hemp-derived CBD topicals – products designed to be applied to the skin – from physical stores and online sites.
Of the 89 labels that list the amount of CBD, for example, 24% matched what was inside; 58% of the products had more CBD; and the remaining 18% contained less.
Also, more than a third – 35% – of the topicals tested contained delta-9-tetrahydrocannabinol (THC), including some that claimed to be THC-free.
THC is the compound in marijuana associated with "getting high." But hemp products are allowed to contain 0.3% or less THC, and all the products in this study met the regulation.
People should "be wary of cannabinoid products available in retail stores. The products may not contain the amounts of CBD or THC that are advertised," says lead study author Tory R. Spindle, PhD.
The study was published in JAMA Network Open on July 20.
Can Be Deceiving
CBD topicals are over-the-counter (OTC) products, so the FDA does not regulate them the same way as prescription medications. But at the same time, the agency does not allow OTC products to make claims about health benefits.
"The health claims made on the products, which are often very pricey, may not be supported by clinical research," says Spindle, a researcher at the Johns Hopkins Cannabis Science Laboratory in Baltimore.
He and colleagues found 28% of the 105 products made a therapeutic claim, mostly about helping ease pain and inflammation. And 14% claimed to help improve skin quality or appearance.
"This study really highlights that current regulatory oversight of cannabinoid products is not sufficient," says Spindle, who is also an assistant professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine.
More hemp-derived CBD products are showing up on store shelves and online because of the 2018 Agriculture Improvement Act. This act, more commonly known as the Farm Bill, removed hemp and hemp products from the U.S. controlled substances list…
For JAMA Research Cannabinoid Content and Label Accuracy of Hemp-Derived Topical Products Available Online and at National Retail Stores JAMA Network Open
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Genetic impact of cannabis on in utero life and subsequent generational harms. Of major concern is the rising Community Cannabis Exposure (CCE) impacting exponential cannabinoid genotoxic dose-response relationships. CCE should be carefully restricted to protect the food chain, the genome, and the epigenome of coming generations
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“Our research demonstrates that cannabis use in the general population is associated with heightened risk of clinically serious negative outcomes, specifically, needing to present to the ED [emergency department] or be admitted to hospital,”
- Cannabis users were 22 percent more likely than those who don’t use to land in the emergency room or become hospitalized for any reason, suggesting use of the drug may be associated with negative health outcomes.
- Bodily injury was the top reason for emergency department visits and hospitalizations among marijuana users, while respiratory issues came in second.
- While recreational marijuana is still illegal in the U.S. under federal law, at least 19 states have passed legislation to allow sales of the drug.
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With the effect of cannabis on some of the parameters being studied for the first time in this study, the researchers discovered that cannabis had a detrimental effect on all of the visual parameters they assessed.
Another study that investigated the effects of smoking cannabis on vision and driving performance also found that the visual effects of cannabis could impact driving performance, jeopardizing driving safety. Overall, it appears that information and awareness initiatives are critical for reducing the prevalence of cannabis-impaired driving.
Source: It's official. Smoking cannabis substantially alters the way you see (interestingengineering.com)
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Delta 8 THC Causing Cancer – Epidemiology of Δ8THC-Related Carcinogenesis in USA: A Panel Regression and Causal Inferential Study
From the Abstract Results indicate that between 8 and 20/34 cancer types were associated with Δ8THC exposure, with very high effect sizes (mEVs) and marginal effects after adjustment exceeding tobacco and alcohol, fulfilling the epidemiological criteria of causality and suggesting a cannabinoid class effect. The inclusion of pediatric leukemias and testicular cancer herein demonstrates heritable malignant teratogenesis. View Full-Text
Research published in https://www.mdpi.com/1660-4601/19/13/7726
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