Get a Clue - Weed

Details: Published: 14 February 2023; Hits: 1136

Conclusions: Accurate and informative labelling of hemp and hemp-derived CBD products is an important public health issue. FDA-regulated product labels are considered an essential tool for protecting consumers and enabling informed decision-making. Untruthful or unsubstantiated health-related claims, and unallowed Drug Claims, in marketing materials and on labels of CBD products may create harm by enticing consumers to forgo more evidence-based medical interventions. Furthermore, missing or inaccurate labelling of the amount of CBD, delta-9 tetrahydrocannabinol (THC), and potentially harmful contaminants such as pesticides, naturally-occurring yeast and mold or heavy metals may result in harm and/or lack of efficacy. Manufacturers of these products may reasonably be expected to understand and adhere to FDA regulations for labelling and marketing of food, dietary supplements and drugs, both over-the-counter (OTC) and prescription, even though FDA has interpreted federal law as excluding them from these categories. As manufacturers prepare for forthcoming regulations, a better understanding of the basic framework for FDA labelling and marketing regulations for food, dietary supplements and drugs is warranted.

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Also see

Heavy metal and phthalate contamination and labelling integrity in a large sample of commercially available cannabidiol (CBD) products
FDA, FTC warn company marketing unapproved cannabidiol products
FDA Says Most CBD Products May Not Be Safe, and Warns 15 Companies to Stop Selling Them
What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD
Dr Robert L Dupont's written Testimony to the FDA Regarding the Health Impacts of CBD

Details: Published: 14 February 2023; Hits: 1122

Geospatiotemporal and Causal Inferential Study of European Epidemiological Patterns of Cannabis- and Substance-Related Congenital Orofacial Anomalies

Conclusion. Rising cannabis use is associated with all the Facial Congenital Abnormalities and fulfils the epidemiological criteria for causality. The data indicate particular concerns relating to brain development and exponential genotoxic dose-responses, urging caution with regard to community cannabinoid penetration.

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Details: Published: 03 February 2023; Hits: 1059

Key Points

Driving under the influence of cannabis has been identified as a public health concern as medical and recreational cannabis availability increases in some countries.
A recent randomized clinical trial found similar levels of acute driving impairment with THC-dominant cannabis and with a combination of THC-CBD equivalent cannabis using on-road driving tests that provided real-world conditions; however, CBD-dominant cannabis did not produce significant cognitive or psychomotor impairment compared with placebo in this trial.
Media coverage of this study conveyed the findings as CBD-dominant cannabis not causing driving impairment while THC-dominant cannabis does, with the latter lasting up to 4 h post-dose.
It is recommended that clinicians counsel about the risks of driving impairment when patients disclose use of cannabis products containing THC.

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Cannabis use altering key functions like three-dimensional vision
“Medicinal” Cannabis & Driving – is it an Issue?

Details: Published: 01 February 2023; Hits: 1204

by Society for the Study of Addiction
A systematic review published today in the scientific journal Addiction has found that cannabis use leads to acute cognitive impairments that may continue beyond the period of intoxication. This Canadian-led meta-review (review of reviews) merged the findings of 10 meta-analyses representing more than 43,000 participants.
The study found that cannabis intoxication leads to small to moderate cognitive impairments in areas including

making decisions,
suppressing inappropriate responses,
learning through reading and listening,
the ability to remember what one reads or hears, and
the time needed to complete a mental task.

These and other acute impairments mirror the residual effects documented for cannabis use, suggesting that the damaging effects of cannabis begin while it is being consumed and persist beyond that period.

For complete Research (medicalxpress.com) and Dellazizzo - 2022 - Addiction - Wiley Online Library

Details: Published: 24 January 2023; Hits: 1061

Exposure to Pro and Anti-Cannabis Social Media Messages and Teens’ and College Students’ Intentions to Use Cannabis

Content analyses have documented that posts about cannabis are increasingly common on social media. The relationship between the cannabis-related content to which teens and college students are exposed on social media and how such content may be associated with intentions to use and use of cannabis is less known, however. We conducted an online survey with teens (N = 350) who lived in Washington state using online survey panel participants in June 2018 and with college students (N = 966) in a Washington state-wide university system in February and March 2019. Participants in both samples reported seeing both pro-cannabis and anti-cannabis messages on social media platforms.

Exposure to pro-cannabis messages on social media was associated with an increased intention to use cannabis.
Exposure to anti-cannabis messages on social media was indirectly associated with decreased intentions to use cannabis through negative outcome beliefs of cannabis use and, among college students, through perceived norms.
Among college students specifically, exposure to pro-cannabis messages on social media was also associated with more frequent cannabis use.
Health communicators could focus anti-cannabis messaging on negative outcome beliefs among teens and college students as well as norms among college students to potentially influence constructs associated with intentions and use.

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