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Published: October 18, 202 3DOI:https://doi.org/10.1016/j.jpain.2023.10.009
Highlights
- CBD products may have varying amounts of CBD, varying from none to much more than advertised.
- CBD products may contain other chemicals than CBD, some of which may be harmful.
- 16 RCTs for pain used pharmaceutical CBD in oral, buccal/sublingual, and topical forms.
- 15 of the 16 RCTs were negative: no greater pain-relieving effect for CBD than for placebo.
- Meta-analyses link CBD to increased rates serious adverse events and hepatotoxicity.
Small clinical trials using verified CBD suggest the drug to be largely benign; while large scale evidence of safety is lacking there is growing evidence linking CBD to increased rates of serious adverse events and hepatotoxicity.
There is no good reason for thinking that CBD relieves pain, but there are good reasons for doubting the contents of CBD products in terms of CBD content and purity.
(for complete research The Journal of Pain – (US Association for Study of Pain, USASP)
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Team of researchers urges further study and evaluation of standards for medical use.
Date: October 20, 2023 Source: University of Tennessee Institute of Agriculture
Summary: Cannabis use, even for medical purposes, could make some people sick due to harmful fungi that contaminate the plants. That is the finding of a recently published peer-reviewed journal article, whose authors recommend further study and consideration of changes to regulations to protect consumers, especially those who are immunocompromised. They examined data, previous studies, and U.S. and international regulations related to the cannabis and hemp industry.
Cannabis research has mostly focused on the substance and medical uses of the plant, but with the increased legalization of cannabis for various uses, this article addresses the need for more study of potential health risks.
"Although fungi and mycotoxins are common and well-studied contaminants in many agricultural crop species, they have been generally under-studied in cannabis and hemp. This is partly because human health risk assessment methodologies used to regulate food and pharmaceuticals have yet to become standard for the emerging cannabis and hemp industries. Additionally, the wide range of consumer uses of cannabis and hemp flowers, including for medical use by patients with susceptible conditions, makes it uniquely challenging to assess and manage human health risk of these contaminants".
(For complete research ScienceDaily)
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This just one individual and health care system crippling outcome of cannabis use is unstainable for any healthcare system, free or paid for. The cannabis lobby and industry continue to deflect, as does the cannabis user, at this growing endemic and the outrageous expense it is incurring on non-drug using tax-payers.
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A new study from Aarhus University Hospital in Denmark has discovered the chronic use of marijuana is linked to as much as a four-fold increase in risk for major depressive disorder, bipolar disorder and associated psychosis.
The news is significant given the rapid increase in US states permitting recreational use of the drug…Although many Americans view pot use as relatively benign, new research is indicating a far greater risk than originally thought.
A study published in the journal Psychological Medicine and sponsored by the National Institutes of Health found a striking link between marijuana use and schizophrenia in young men, with indications use of the drug may be responsible for as much as 30% of cases. There was a similar link for females, but at a far lower rate, roughly 4%.
However, when the age cohort is lowered, indications are that there is a six-times greater risk for schizophrenia among teens who use the drug as little as once a week. The study, published in the Journal of Clinical Psychology, examined marijuana use across the globe.
New research from University of Washington and Kaiser Permanente Washington Health Research Institute estimates 21 percent of marijuana users had become addicted. The National Institute for Drug Abuse, (NIDA) has estimated that at least four million Americans have developed “marijuana use disorder” since cannabis became more widely available.
New Study: Marijuana Use Presents Four Times Higher Risk of Serious Mental Health Consequences
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T.H.C – The Human Consequences: Why legalisation is a public and personal health nightmare.