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The FDA is working to answer questions about the science, safety, and quality of products containing cannabis and cannabis-derived compounds, particularly CBD.
- The FDA has approved only one CBD product, a prescription drug product to treat two rare, severe forms of epilepsy.
- It is currently illegal to market CBD by adding it to a food or labeling it as a dietary supplement.
- The FDA has seen only limited data about CBD safety and these data point to real risks that need to be considered before taking CBD for any reason.
- Some CBD products are being marketed with unproven medical claims and are of unknown quality.
- The FDA will continue to update the public as it learns more about CBD.
- CBD has the potential to harm you, and harm can happen even before you become aware of it.
- CBD can cause liver injury.
- CBD can affect the metabolism of other drugs, causing serious side effects.
- Use of CBD with alcohol or other Central Nervous System depressants increases the risk of sedation and drowsiness, which can lead to injuries.
- CBD can cause side effects that you might notice. These side effects should improve when CBD is stopped or when the amount ingested is reduced.
- Changes in alertness, most commonly experienced as somnolence (drowsiness or sleepiness).
- Gastrointestinal distress, most commonly experienced as diarrhea and/or decreased appetite.
- Changes in mood, most commonly experienced as irritability and agitation.
- There are many important aspects about CBD that we just don’t know, such as:
- What happens if you take CBD daily for sustained periods of time?
- What is the effect of CBD on the developing brain (such as children who take CBD)?
- What are the effects of CBD on the developing fetus or breastfed newborn?
- How does CBD interact with herbs and botanicals?
- Does CBD cause male reproductive toxicity in humans, as has been reported in studies of animals?
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BU researcher finds that miscarriages are more likely when the father uses marijuana weekly - If a man habitually uses marijuana even as little as once a week, could that increase the risk of his partner experiencing a miscarriage in early pregnancy? A first-of-its-kind study suggests so.
By analyzing more than six years of lifestyle and behavioral data from 1,535 heterosexual couples actively trying to conceive, Boston University School of Public Health researcher Alyssa Harlow discovered that for men who use marijuana one or more times a week, their partner is twice as likely to miscarry than the partners of men who use marijuana less than once a week or not at all. The link persisted even after Harlow accounted for whether or not the men’s partners used marijuana themselves.
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Teenagers suffer higher rates of addiction when recreational cannabis is legalised - study
New research about legal cannabis has revealed a sobering statistic. In states where recreational marijuana has been legalised, teenagers are suffering higher rates of addiction.
The study of 505,796 respondents was carried out by researchers from New York University's School of Medicine.
It compared use of the drug before and after legalisation in the US.
The proportion of people aged 12 to 17 who reported cannabis use disorder grew from 2.18 percent to 2.72 percent.
Chris Wilkins, a senior drug researcher at Massey University says the research is a "red flag".
"It's an indicator, it's definitely a red flag given the negative trajectories when people use cannabis at that young age," he told The AM Show on Thursday.
The Study: Association Between Recreational Marijuana Legalization in the United States and Changes in Marijuana Use and Cannabis Use Disorder From 2008 to 2016
JAMA Psychiatry. Published online November 13, 2019. doi:https://doi.org/10.1001/jamapsychiatry.2019.3254
Key Points
Question How did marijuana use and cannabis use disorder change during 2008 to 2016 after the legalization of recreational marijuana in the United States?
Findings: In this multilevel, difference-in-difference survey study with 505 796 respondents comparing marijuana use before and after the legalization of recreational marijuana in the United States, the proportion of respondents aged 12 to 17 years reporting cannabis use disorder increased from 2.18% to 2.72%, while the proportion of respondents 26 years or older reporting frequent marijuana use increased from 2.13% to 2.62% and those with cannabis use disorder, from 0.90% to 1.23%.
Meaning: This study’s findings suggest that possible increases in the risk for cannabis use disorder among adolescent users and increases in frequent use and cannabis use disorder among adults after legalization of recreational marijuana use may raise public health concerns and warrant ongoing study.
Conclusions and Relevance: This study’s findings suggest that although marijuana legalization advanced social justice goals, the small post-RML increase in risk for CUD among respondents aged 12 to 17 years and increased frequent use and CUD among adults 26 years or older in this study are a potential public health concern. To undertake prevention efforts, further studies are warranted to assess how these increases occur and to identify subpopulations that may be especially vulnerable.
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Medical Xpress: Frequent cannabis (marijuana) use among young people was linked to an increased risk of stroke and people diagnosed with cannabis use disorder were more likely to be hospitalized for heart rhythm disturbances (arrhythmias), according to two new preliminary studies to be presented at the American Heart Association's Scientific Sessions 2019
"The effects of using cannabis are seen within 15 minutes and last for around three hours. At lower doses, it is linked to a rapid heartbeat. At higher doses, it is linked to a too-slow heartbeat," said Rikinkumar S. Patel, M.D., M.P.H., resident physician in the department of psychiatry at the Griffin Memorial Hospital in Norman, Oklahoma.
"The risk of cannabis use linked to arrhythmia in young people is a major concern, and physicians should ask patients hospitalized with arrhythmias about their use of cannabis and other substances because they could be triggering their arrhythmias," said Patel.