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QUESTION: What do these deadly poisons have in common: arsenic, radium, mercury, thallium, cyanide?
ANSWER: At one time they were all considered by physicians and the public as useful medications and/or healthy supplements. They were taken in a wide variety of lotions, potions, notions, tinctures, tonics, and pills. These poisons were recommended, sold, and prescribed freely by physicians.1 It took thousands of deaths and many decades before the harmful nature of these substances was perceived by physicians and the general public.
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International Journal of Stroke : Official Journal of the International Stroke Society
- The authors of this study examined stroke-related hospitalizations and outcomes in cannabis users aged 18 to 49 years from 2007 to 2014. They evaluated records from over 3 million hospitalizations and identified 34,857 hospitalizations for young-onset stroke. Compared with non-cannabis users, cannabis users had increases in all strokes (OR, 1.16; P<.001) and acute ischemic strokes (OR, 1.41; P<.001). From 2007 to 2014, there was a 13.92% increase in stroke admissions associated with cannabis use (P<.001).
- This study has limitations inherent to retrospective studies. Cannabis use is often associated with poor diet and lifestyle, and this study cannot determine the effects of these confounders. It is important for neurologists to recognize the increased risk of stroke among young cannabis users.
– Kyle Binder, MD
CONCLUSIONS
We identified rising trends and higher risk (16% higher of overall young-onset stroke, 41% higher of acute ischemic stroke) of stroke-related hospitalizations and worse outcomes among cannabis users aged 18-49 years from 2007 to 2014.
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Highlights
- Genetic background affects the outcome of adolescent cannabis exposure
- THC exposure increases heroin reinforcing properties in LEW addiction prone rats
- LEW, but not F344 rats, show increased motivation for heroin following THC
- THC exposure increases reinstatement by cues in F344 and by priming in LEW rats
- A common liability mechanism might be at the basis of THC gateway effect
https://www.sciencedirect.com/science/article/abs/pii/S002839082030040X (2020)
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Highlights
- We estimate that >2 million U.S. adults who have reported ever using marijuana have cardiovascular disease.
- Observational studies have suggested an association between marijuana use and a range of cardiovascular risks.
- Marijuana is becoming increasingly potent, and smoking marijuana carries many of the same cardiovascular health hazards as smoking tobacco.
- Few randomized clinical trials have been conducted or are planned to explore the effects of marijuana on cardiovascular risk.
- Screening and testing for use of marijuana are encouraged in clinical settings, especially in the care of young patients presenting with cardiovascular disease
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January 16, 2020
People who use cannabis every day account for more than 80 per cent of the total amount of the drug consumed in Australia, a University of Queensland study has discovered.
The finding suggests there are serious implications for a small group of people if there is a move to decriminalise or fully legalise the drug.
UQ researchers examined data from the National Drug Strategy Household Survey between 2007 and 2016.
A UQ study has found a small proportion of daily cannabis users account for over 80 per cent of the total consumption of the drug in Australia.
(This follows classic dependence consumption modelling – 80% of product consumed by small amount – Industry makes most of its money off addiction for profit. Dalgarno Institute)
- Marijuana detected in homicide victims nearly doubles: Over two-thirds of adolescent victims aged 15-20 tested positive in 2016
- Marijuana use during pregnancy can negatively affect baby, landmark Western University study finds (17.1.2020)
- The New Cannabis: What You Aren’t Being Told!
- State-Based Drug Use Survey Finds Marijuana Use Skyrocketing in "Legal" States