(partae - vaping)
Association of 1 Vaping Session With Cellular Oxidative Stress in Otherwise Healthy Young People With No History of Smoking or Vaping-A Randomized Clinical Crossover Trial
A single 30-minute vaping session can significantly increase cellular oxidative stress. Middlekauff et al demonstrated that vaping is associated with adverse changes in the body that can presage future health problems
Like tobacco cigarette (TCIG) smoking, long-term electronic cigarette (ECIG) vaping in young people is associated with elevated cellular oxidative stress (COS), which is important in the pathogenesis of many diseases, including atherosclerosis.1 As with TCIG smoking,2 even infrequent ECIG use may be associated with adverse biological effects with implications for future health risks. Importantly, the proportion of high school students who have used ECIGs within 1 month of the time of study has skyrocketed, approaching 30% in the US.3,4 The purpose of this study was to evaluate the association of a single session of ECIG vaping on COS in immune cells in young people who do not smoke or vape compared with young people with long-term TCIG or ECIG use.
Introduction The rising popularity of TikTok among adolescents may influence their awareness and perceptions of e-cigarette use via user-generated content. This study aimed to examine how e-cigarette/vaping-related videos are portrayed on TikTok.
Methods The nine most viewed hashtag based keywords were used to identify popular e-cigarette/vaping-related videos on TikTok (n=1000) from its inception (earliest upload date: January 2019) to November 2020. Five researchers independently coded the number of views, likes, user category and theme.
Results A final sample of 808 e-cigarette/vaping-related videos that met study criteria were included. Collectively, these videos were viewed over 1.5 billion times, with a median view count of 1 000 000 (range 112 900–78 600 000) and a median ‘likes’ count of 143 000 (range 10 000–1 000 000). A majority of the videos portrayed e-cigarette use positively (63%; collectively viewed over 1.1 billion times). Neutral depictions of e-cigarette use were viewed a total of 290 million times (24%) and negative depictions of e-cigarettes were viewed a total of 193 million times (13%). The video themes included (not mutually exclusively): ‘comedy and joke’ (52%; total of 618 million views), ‘lifestyle and acceptability’ (35%; 459 million), ‘marketing’ (29%; 392 million), ‘vaping tricks’ (20%; 487 million), ‘nicotine and addiction’ (20%; 194 million), ‘creativity’ (16%; 322 million) and ‘warning’ (11%; 131 million).
Conclusion Our findings illustrated that positively framed e-cigarette and vaping-related postings available without age restrictions on TikTok—a rising video-sharing platform that is popular among adolescents—have been viewed many times. Effective age restrictions are needed to reduce adolescents’ potential exposure to videos that portray vaping positively.
Nitrite “poppers” are not the same as chicken poppers, pizza poppers, or cheesy corn poppers. While you can still use the latter three for recreation or sexual enhancement, the U.S. Food and Drug Administration (FDA) is warning that you should not use nitrite “poppers” for such purposes. That’s because nitrite “poppers” can lead to all sorts of bad health effects, including death. And death, for most people, is not good for sex.
Relaxing your smooth muscles with “poppers” can be hazardous though. After all, your body is more than just your anus or vagina. Dropping your blood pressure can mean that different parts of your body may not get enough blood and oxygen. Alkyl nitrites can lead to methemoglobinemia too. This is where your body produces an abnormal amount of methemoglobin. Methemoglobin is a form of hemoglobin. Hemoglobin is the protein in red blood cells (RBCs) that normally picks up oxygen from your lungs, carries it via the bloodstream, and then releases the oxygen to your body tissues. The problem is the methemoglobin form of hemoglobin, in the words of Mariah Carey, can’t let go. It can’t really release the oxygen to your body tissues, effectively starving these tissues of oxygen.
Therefore, it’s not a complete surprise that the FDA has, in their words, “observed an increase in reports of deaths and hospitalizations with issues such as severe headaches, dizziness, increase in body temperature, difficulty breathing, extreme drops in blood pressure, blood oxygen issues (methemoglobinemia) and brain death after ingestion or inhalation of nitrite ‘poppers.’” Death will, of course, really relax your anus and vagina but has other consequences.
The risk of bad effects jumps even higher when you combine poppers with other substances that can also dilate your blood vessels. These substances include blood pressure medications, sildenafil (Viagra), and alcohol. But, of course, no one mixes alcohol or Viagra with sex, right?
The FDA warned specifically about using nitrite “poppers” for recreational purposes or sexual enhancement.
Also see Truth About Poppers
In a recent article in Queensland’s Courier Mail, It literally melts kids’ brains the issue of ‘chroming’ or inhalant use has been put back on the public radar. Whilst this issue has never disappeared, it does come to public attention when harms grow.
Hospitalisations for teenagers suffering from chroming sickness have increased for the fifth straight year as a teacher’s call to ban an aerosol deodorant linked to the devastating habit goes unheard.
Hospitalisations have increased by 40 per cent among people under 19 and are up 11 per cent overall from the 2018/19 to 2019/20.
There were 115 people put in Queensland hospitals 157 times due to chroming, 63 of them were 19 years and under.
Queensland Children’s Hospital Emergency Physician Dr Daniel Bodnar has seen the increase first-hand with children as young as 12 hospitalised for chroming related illness.
“What really worries me is the long-term effects, these solvents are like paint strippers, and much like a paint stripper melts the paint off a paint brush, that’s what it does to people’s brains,” Dr Bodnar said.
“It literally melts the special lining of the nerve cells in the brain which leads to major problems down the track like they can’t think properly and their IQ goes down,” he said.
“The brain is very slow to heal and the idea is the more exposed to it the more likely long term damage will be done,” he said.
“It’s just horrible, you can actually see evidence of it on scans.”
Inhalant issues can come and go, depending on several influencing factors and their potential influence on use. For example, the 2007 ‘Graffiti Prevention Act’ (Victoria that came into effect in 2008) saw the restrictions on sales of spray paint to minors. The term ‘Chroming’ was synonymous with inhalant activity with spray paint products being the primary, but not sole source of inhalant activity.
Dalgarno Institute staff have had firsthand experience with young people who used inhalants extensively prior to this injunction, and the fatal capacity of inhalant use, with one young 16 y.o client dying on a train station platform after a single inhalant episode.
Other factors can contribute to decline in use, such as easier access to other illicit drugs or cheaper and easily accessible alcohol. If other substances are either more readily available, cheaper, or easier to access, this can divert from inhalant use.
Of course, determinants of engagement with inhalant or another our mood/mind altering substance remain many and varied.
Whilst trauma, neglect and abuse can be key social determinants of use, so are other factors such as tacit permission modes for substance engagement that pro-drug advocates are promulgating via ‘inevitability’ and even ‘right’ messaging on substance use. Also underlying much of the substance engagement issue remains, meaninglessness, purposelessness and the boredom and hedonic activities these can precipitate.
‘Grown Ups’ and Inhalants.
Inhalant use is not the purview of the hapless teen alone. There are more ‘sophisticated versions’ of inhalant use in the marketplace parading as psycho-social and psycho-sexual enhancement vehicles. One common genre is ‘Poppers’.
This chemical amyl nitrite has been prescribed by doctors in the past to people with heart conditions. Whilst currently it is used to treat cyanide poisoning.
Yet, this inhalant may also be ‘embellished’ with various chemicals and can be cryptically marketed as a ‘room deodorizers’ or ‘leather cleaners’. However, in certain jurisdictions, it can be sold as a ‘party supplement’ such as Jungle Juice Platinum or Double Scorpio Honey.
In the summary of a 2020 Medical News Today Article, the risks of harms from this substance are very concerning;
Poppers can cause serious side effects, and some reactions can be fatal. Considering the possible adverse effects, the best option is not to use poppers. The risks outweigh the short-lived high of the drug.
Personal stories of short and long-term harms of this inhalant are real, growing, and disturbing.
One website dedicated to warning against this inhalant use is The Truth About Poppers and is aimed at not only creating awareness but providing a forum for those who have experienced the harms of this dangerous practice and want to warn their friends and loved ones of the harms of this substance.