Get a Clue

(Weed)

Pin It

Earlier this year, our laboratory published work demonstrating that rats whose mothers were given low-dose THC (or an analogous synthetic cannabinoid) while pregnant showed significant changes in synaptic plasticity and altered levels of several important proteins lasting well into adulthood. We found that the consequences of these changes manifested as a reduced sociability in the exposed offspring. Male rats in particular were much less likely to approach, play with, or sniff other rats.4

These findings parallel sociobehavioral changes seen in young adult humans exposed to cannabis during gestation. And scientists are now linking those effects to changes in the brain that are similar to what we observed in rats. Using functional MRI technology, for example, researchers participating in the Ottawa Prenatal Prospective Study observed a reduction in activity in the prefrontal cortices of adult offspring of mothers who smoked marijuana during pregnancy. This drop was associated with decreased working memory, echoing the attentional problems and memory dysfunction seen as early as infancy.5

Cannabis is also likely to affect the amygdala, which is critical for emotional development. In 2004, Yasmin Hurd of the Karolinska Institute and colleagues identified a significant reduction in dopamine D2 receptor mRNA in the amygdalae of fetal brains that correlated with the reported quantity of cannabis consumed by their mothers.6 (The fetuses were all between 18 and 22 weeks of gestation and donated by women who underwent voluntary abortions.) Given the known role of amygdala dopamine signaling in the regulation of mood and emotion, these findings could explain the increased depressive-like symptoms observed in children following cannabis exposure in utero, as well as these kids’ propensity towards inattention and impulsivity.

The problem of infant cannabis exposure extends well beyond pregnancy. THC and its lipophilic cannabinoid analogs are readily transferred through breast milk of humans and other mammals, and animal studies have pointed to these compounds’ influence on development throughout the pre-weaning period. Worse yet, given that these cannabinoids linger in the body for weeks, the “pump-and-dump” approach often employed to avoid feeding alcohol-laden milk to an infant isn’t as effective for cannabis users—a Friday night joint can continue to deliver active cannabinoids through breast milk throughout the weekend and into the next week.

For complete study and comprehensive analysis go to  THE SCIENTIST 2019 and Marijuana for Morning Sickness a Mistake!

 

SAM

 

Frequently Asked Questions of Why We Are Opposed to Weed!

Get ya head straight!

Read More Now

cannabis info support

marvscn 350

 

video thumb

Marijuana Victims' Association
Windsor Morning

Busting the Myth
that Cannabis Doesn't Kill

  View Video 

Dr Kevin Sabet, C.E.O of Smart Approaches to Marijuana: Presents at the 20th NADCP Annual Conference

  View Video

The Marijuana-Opioid Connection

  View Video

 

HARMFUL EFFECTS

sidebar add1

 SkunkCannabis

We provide a range of tools for educators to help deal with the issues of alcohol & other drugs
We provide a range of resources to help you deal with the issues of alcohol & other drugs
Find out what is happening in the world of alcohol & other drugs
Check out our selection of video clips on various topics

 Need Help?

  • Looking for help or at least thinking you really might need it?
  • Feeling a bit lost and alone and running out of options?
  • Maybe you're even thinking there is no way out?
  • well, you don't have to hit bottom to start looking for better options, pick up the phone and talk to somone who gives a damn.

Contact Help Line today...

Call 03 9583 2273 most times

Address:
PO Box 7005,
Dandenong, Vic, 3175
Telephone: 1300 975 002

Powered by Dalgarno Institute

logo header