Nature Medicine volume 26, pages1536–1540 (2020)
Abstract: Cannabis use in pregnancy has increased1,2, and many women continue to use it throughout pregnancy3. With the legalization of recreational cannabis in many jurisdictions, there is concern about potentially adverse childhood outcomes related to prenatal exposure4. Using the provincial birth registry containing information on cannabis use during pregnancy, we perform a retrospective analysis of all live births in Ontario, Canada, between 1 April 2007 and 31 March 2012. We link pregnancy and birth data to provincial health administrative databases to ascertain child neurodevelopmental outcomes. We use matching techniques to control for confounding and Cox proportional hazards regression models to examine associations between prenatal cannabis use and child neurodevelopment. We find an association between maternal cannabis use in pregnancy and the incidence of autism spectrum disorder in the offspring. The incidence of autism spectrum disorder diagnosis was 4.00 per 1,000 person-years among children with exposure compared to 2.42 among unexposed children, and the fully adjusted hazard ratio was 1.51 (95% confidence interval: 1.17–1.96) in the matched cohort. The incidence of intellectual disability and learning disorders was higher among offspring of mothers who use cannabis in pregnancy, although less statistically robust. We emphasize a cautious interpretation of these findings given the likelihood of residual confounding.
Associations Between Prenatal Cannabis Exposure and Childhood Outcomes
Findings: This cross-sectional analysis of 11 489 children (655 exposed to cannabis prenatally) found that prenatal cannabis exposure after maternal knowledge of pregnancy was associated with greater psychopathology during middle childhood, even after accounting for potentially confounding variables.
Meaning: Prenatal cannabis exposure may increase risk for psychopathology; consistent with recent recommendations by the Surgeon General of the United States, these data suggest that cannabis use during pregnancy should be discouraged by clinicians and dispensaries.
Conclusions and Relevance: This study suggests that prenatal cannabis exposure and its correlated factors are associated with greater risk for psychopathology during middle childhood. Cannabis use during pregnancy should be discouraged.
Review of Book Cannabis as Medicine – An Evidence-Based Approach by Dr K Finn (Reviewed by: J. Michael Bostwick, MD, Professor of Psychiatry, Mayo Clinic, Rochester, MN)
“The book can also serve as a primer on what is known about cannabis as medicine, keeping in mind a slant throughout – not necessarily unjustified, at least from an allopathic or osteopathic perspective – that cannabis is neither legitimate as medicine nor safe, even for recreational use.”
SOCIETY FOR THE STUDY OF ADDICTION
A study published in the scientific journal Addiction suggests that, contrary to what some are claiming, people in the US may not be substituting cannabis for opioids.
This study examined the direction and strength of association between cannabis and opioid use over 90 consecutive days. Among adults who used non-medical opioids, the study compared the probability of non-medical opioid use on days when cannabis was used with days when cannabis was not used. The study included 13,271 days of observation among 211 participants from the greater New York area.
Study co-author, Deborah Hasin, states, "Our study is among the first to test opioid substitution directly, suggesting that cannabis seldom serves as a substitute for non-medical opioids among opioid-using adults, even among those who report experiencing moderate or more severe pain. In other words, our study suggests that cannabis is not an effective way
For complete article go to Pro-Pot Propaganda Popped!
For Research go to Is Cannabis being used as a substitute for non‐medical opioids by adults with problem substance use in the United States? A within‐person analysis
Missouri Medicine: Medical Fraud, Mislabelling, Contamination: All Common in CBD Products – Glaucoma Made Worse by Marijuana – Other Critical Reviews of Unscientific Cannabis Claims